Something

on *:text:*jared*:#:{
if ($address($nick,2) isin %hilightresponse) { halt }
  if ($address($nick,2) isin %hilightignore) { 
    set %hilightresponse %hilightresponse $address($nick,2) 
  notice $nick 1You're ignored by my highlights :D - one time response | halt }
  join $chan 
}

on *:input:*:{
  if ($1 == +ignore) { 
    if ($address($2,2) isin %hilightignore) { echo $2 is already in the ignore list | halt }
    set %hilightignore %hilightignore $address($2,2)
    echo $2 has been added to highlight ignore list.
  }
  if ($1 == -ignore) {
    if ($address($2,2) isin %hilightignore) {
      set %hilightignore $remove(%hilightignore,$address($2,2))
      echo $2 has been deleted from highlight ignore list.
      set %hilightresponse $remove(%hilightignore,$address($2,2))
    }
    else echo $2 is not in your highlight ignore list |  halt
  }
}