Something

var.basedir  = "/var/www/localhost"
var.logdir   = "/var/log/lighttpd"
var.statedir = "/var/lib/lighttpd"
server.modules = (
   "mod_alias",
   "mod_access",
#  "mod_magnet",
#  "mod_setenv",
   "mod_accesslog"
)

include "mime-types.conf"
include "mod_cgi.conf"
  
server.username      = "lighttpd"
server.groupname     = "lighttpd"

server.document-root = var.basedir + "/htdocs"
server.pid-file      = "/var/run/lighttpd.pid"

server.errorlog      = var.logdir  + "/error.log"

server.indexfiles    = ("index.php", "index.html",
			"index.htm", "default.htm")

server.follow-symlink = "enable"

alias.url += (
     "/otrs-web"		=>	"/opt/otrs/var/httpd/htdocs",
     "/otrs"			=>	"/opt/otrs/bin/cgi-bin"
)
$HTTP["url"] =~ "^/otrs" {
	cgi.assign = ( "" => "")
	index-file.names=("index.pl")
}