Something

<VirtualHost 127.0.0.1:80>
        <Location />
                Order allow,deny
                Allow from all
                SetHandler perl-script
                PerlHandler Foo
        </Location>

        <LocationMatch "/promos/*">
                SetHandler none
                PerlHandler -Foo
        </LocationMatch>
        <Directory "/home/blah/promos/*">
                SetHandler none
                Options +Indexes
        </Directory>

        <LocationMatch  "/(phpBB*|somthingelse*|promos*||andthenthis*)">
                SetHandler none
        </LocationMatch>
</VirtualHost>