The ultimate knowledge is the knowledge of self. If this is to be taken to it's logical end, it is in fact the only knowledge. What we know about everything that we see, do, crave, loose, love, envy, and any continuum of words you care to mention, is only so that one may come to know oneself.
Science is but on branch of the exquisite search for the lonely finite within a devine infinite. To lock oneself into a singularity is assured destruction.
We must seek to disperse, to diversify, to question and to mock. Above all we should seek to be known.
The human race is a mirror: looking into it one may see a myriad of shattered reflections. Tiny burning sparks of recognition, of empathy, within a deep dark sea of intrigue.
This is the dichotomy of duality, the single embodied element of an unimaginable cohesive mass.
If you seek to know yourself, know that you are the sum of an equation too explosive to contain. So much so that every fiber or your immortal being ressonates through the devine coil as an element of us: the one's you will never know, but will always be.