Someone

#!/usr/bin/env python 
import gtk
import gobject

class MyTextView(gtk.TextView):
    __gsignals__ = dict(
        mykeypress = (gobject.SIGNAL_RUN_LAST | gobject.SIGNAL_ACTION,
                    None, # return value
                    (str,)) # arguments
        )
if gobject.pygtk_version < (2, 8):
    gobject.type_register(MyTextView)

gtk.binding_entry_add_signal(MyTextView, gtk.keysyms.f, gtk.gdk.CONTROL_MASK, 'mykeypress', str, 'ctrl+f')

def activate_cb(tv, what):
    print 'You pressed', what

tv = MyTextView()
tv.connect('mykeypress', activate_cb)
w = gtk.Window()
w.add(tv)
w.set_default_size(400, 300)
w.show_all()
w.connect('destroy', lambda w: gtk.main_quit())
gtk.main()