http://www.jnutbio.com/article/S0955-2863%2809%2900031-X/abstract
>adiponectin upregulated in response to intermittent fasting in rats
http://jap.physiology.org/content/103/2/547.short
> Alternate-day fasting protects against uncontrolled cell proliferation and lowers IGF-1 levels in vitro and in rats, reduces risk of cancer
http://www.ajcn.org/content/85/4/981.short
> one meal a day, without restricting calories, improves wide variety of health markers
http://jap.physiology.org/content/99/6/2128.long
> 15 days of intermittent fasting upregulate adiponectin and improve leptin action and insulin sensitivity
http://diabetes.diabetesjournals.org/content/55/9/2562.short
> adiponectin (a product of fasting) upregulates AMPk action, fatty acid oxidation, PPAR anti-oxidant activity, and p38 - all markers correlated to reduced cancer/obesity rates
http://diabetes.diabetesjournals.org/content/51/6/1884.short
> adiponectin repairs damaged insulin receptors, improves full body insulin sensitivity
I have waaaaaayyyy more to come....
[ - ] Cellbio !EtMMUKvKeA 03/05/12(Mon)03:30 No.11441138 [ ! ] >>11441182
http://www.sciencedirect.com/science/article/pii/S0303720709004389
> article discussing the endocrine action of fat. Talks about how fat tissue is sensitive to changes in AMP/ATP ratio, which in turn upregulates AMPk in fat tissue, eventually resulting in transcriptional changes that upregulate serum adiponectin levels.
> FOXO activation, a downstream product of AMPk in adipose tissue, upregulates adiponectin gene transcription and therefore adiponectin secretion
http://www.jbc.org/content/281/52/39915.abstract
http://www.jbc.org/content/279/29/30817.long
> adiponectin receptors significantly increased in fasted mice and significantly reduced in fed mice
http://www.ncbi.nlm.nih.gov/pubmed/12574632
> nitric oxide production, a product of epinephrine, epinephrine being a response to fasting, improves rates of mitochondrial biogenesis
http://onlinelibrary.wiley.com/doi/10.1002/hep.20821/full
> adiponectin protects against oxidative damage saturated fat in epithelial cells.
still a lot more to come. is anyone even interested?
Just to follow up.
http://journals.lww.com/anesthesiology/Abstract/2004/04000/Acute_Hyperinsulinemia_Restrains_Endotoxi
n_induced.16.aspx
> Acute Hyperinsulinemia under normoglycemic conditions reduces inflammatory markers TNFa and IL-6
http://www.sciencedirect.com/science/article/pii/S0026049598900312
> homocysteine levels reduced by acute hyperinsulinemia in healthy non-diabetics but no change in diabetics
http://diabetes.diabetesjournals.org/content/42/6/833.short
> short term hyperinsulinemia reduces VLDL size and triglyceride levels in healthy subjects, but not in obese subjects
continuing link dump...
http://www.jbc.org/content/282/11/7991.long
> adiponectin inhibits p70s6k, a damager of insulin receptors, and restores insulin sensitivity via AMPK upregulation
http://care.diabetesjournals.org/content/27/2/629.long
> exercise upregulates adiponectin by 260%, but only takes 3 weeks to reach peak levels.
http://jap.physiology.org/content/99/6/2128.short
> 15 days of 20h/day fasts upregulate adiponectin by 65% in healthy males, improve insulin action
http://carcin.oxfordjournals.org/content/23/5/817.short
> 1 day/week fasts have same cancer-preventing effects as calorie restriction. However, IF doesn't drastically lower leptin or IGF-1 levels.
http://onlinelibrary.wiley.com/doi/10.1111/j.1467-789X.2006.00207.x/abstract
> Intermittent fasting has stronger anti-cancer/obesity actions than calorie restriction, as well as better adherence
http://www.sciencedirect.com/science/article/pii/S001457930700155X
> Intermittent fasting decreases morbidity and death rates in Type I diabetic rats by improving biochemical pathways related to p38, p53 and Sir2.
http://ajpendo.physiology.org/content/288/5/E965.short
> 5% calorie restriction + IF performs just as well as 33% calorie restriction sans IF in combating cancerous cell proliferation.
http://onlinelibrary.wiley.com/doi/10.1111/j.1749-6632.2009.04019.x/abstract
>FOXO and AMPK upregulation (two products of IF) increase longevity.