Something

[mysqld]
datadir=/var/lib/mysql
socket=/var/lib/mysql/mysql.sock
skip-locking
skip-external-locking
back_log = 75
#skip-innodb
max_connections = 750
key_buffer = 384M
myisam_sort_buffer_size = 128M
join_buffer_size = 1M
read_buffer_size = 1M
sort_buffer_size = 2M
table_cache = 1800
thread_cache_size = 384
wait_timeout = 7200
connect_timeout = 10
tmp_table_size = 64M
max_heap_table_size = 64M
max_allowed_packet = 64M
max_connect_errors = 1000
read_rnd_buffer_size = 524288
bulk_insert_buffer_size = 8M
query_cache_limit = 4M
query_cache_size =128M
query_cache_type = 1
query_prealloc_size = 65536
query_alloc_block_size = 231072
#default-storage-engine = MyISAM

[mysql.server]
user=mysql
basedir=/var/lib

[mysqld_safe]
nice = -5

open_files_limit = 10240
err-log=/var/log/mysqld.log
pid-file=/var/run/mysqld/mysqld.pid

[mysqldump]
quick
max_allowed_packet = 16M

[myisamchk]
key_buffer = 64M
sort_buffer = 64M
read_buffer = 16M
write_buffer = 16M